Oxidation of Carbamazepine by Potassium Permanganate
This research focuses on characterizing the kinetics of reactions between potassium permanganate (KMnO4) and carbamazepine, a widely prescribed anticonvulsant drug that has been detected in water bodies. Although many drinking water utilities use KMnO4 for pre-oxidation of source waters (e.g., for control of taste-and-odor compounds), little is known about the fate of pharmaceutical micropollutants during permanganate treatment. Batch experiments were conducted to quantify reaction rates under different water quality conditions (e.g., pH). Reaction data was fit with a pseudo-first order kinetic model, where the disappearance of permanganate was monitored in the presence of excess carbamazepine. The reaction was found to be second order. It showed no dependence on pH (5.5-9.0), on temperature or on the addition of NOM and HCO3-. Results from this research can be used to predict the extent to which carbamazepine is oxidized during permanganate treatment processes in water treatment facilities.
School:
University of Puerto Rico at Bayamón
Department:
Human Biology
Research Advisor:
Timothy Strathmann
Department of Research Advisor:
Civil and Environmental Engineering
Year of Publication:
2006