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Osteoporosis: Calcium intake validation and heel ultrasound

Objective: 1. It is well documented that calcium intake plays a significant role in the risk of osteoporosis. The goal of the first part of this study is to validate a food intake record for calcium. 2. Monitoring bone density as a means of screening for osteoporosis is a useful tool in the prevention of this disease. The second part of this study will be obtaining broadband ultrasound attenuation (BUA) as a means of screening for bone density as a risk factor for osteoporosis.

Design: 1. Calcium intake will be recorded using two methods. First, a food frequency survey will be developed and pilot-tested for face validity. Then a calcium rich food frequency survey will be compared to 24-hour food recall data obtained from large convenience sample. This will be used to validate the calcium-rich food frequency survey. 2. Bone density data will be obtained from a convenience sample of adult women by BUA.

Subjects: For both parts of this study Caucasian and African American adult women representative of pre, per, and postmenopausal life stages will be used.

Main Outcome Measures: 1. A mean for daily calcium intake will be obtained. 2. BUA, sound of speed (SOS), and a quantitative index (QUI/stiffness) will be collected by heel ultrasound to asses an estimated Bone Mineral Density (BMD).

Statistical Analyses: 1. Calcium intake will be calculated from both the calcium-rich food frequency survey and the 24-hour recall of participants. Group correlation and individual paired t-test will be used to determine the validity and usefulness of the calcium-rich food survey. 2.Descriptives statistics of the ultrasounds variables will be run, along with analysis of variances to determine if there are differences on age category or ethnicity.

Results and Conclusion: 1. We hope to see that the new food frequency survey, which includes calcium-fortified foods, will accurately account for calcium intake of participants. 2. We hope to see the variations in BUA amongst women of different ethnicities.
Author: 
Akpene Ama Atiedu
School: 
University of Illinois at Urbana-Champaign
Department: 
Human Nutrition
Research Advisor: 
Karen Chapman-Novakofski
Department of Research Advisor: 
Food Science and Human Nutrition
Year of Publication: 
2002
The Graduate College at the University of Illinois Urbana-Champaign 801 South Wright Street 204 Coble Hall, MC-322 Champaign, IL 61820-6210 Phone: (217) 333-0035 Fax: (217) 333-8019